Olga Belozerova on Leukoformula

Canine Hemophagocytic Histiocytic Sarcoma: Cytology

Wed, 02 Jul 2025 09:16:09 +0300

🔬 Hemophagocytic Histiocytic Sarcoma in a Dog: Lymph Node and Bone Marrow Cytology 📍 Clinical Case: Mixed-breed dog, female, 7 years old. Moderate regenerative anemia and moderate thrombocytopenia. 🧪 Cytology: First 4 photos — mesenteric lymph node aspirate. Next 6 photos — bone marrow biopsy. 🧫 Conclusion: 📌 Hemophagocytic histiocytic sarcoma in both locations. 📌 Bone marrow: marked erythroid hyperplasia (ineffective) and megakaryocytic hyperplasia. 📌 Thrombocytopenia of non-central origin.

Canine Small Cell Lymphoma: Lymph Node Cytology

Tue, 02 Jan 2024 20:00:00 +0300

🔬Small cell lymphoma. Aspirate from enlarged superficial lymph nodes in a middle-aged dog. In two cases in my practice, small cell lymphoma was diagnosed in American Staffordshire Terriers.

Canine Acute Lymphoid Leukemia: Blast Morphology

Sun, 10 Dec 2023 10:00:01 +0300

🔬🩸🐕Blood of a 7-year-old female mixed-breed dog. Referred for investigation of anemia and possible piroplasmosis; symptoms unknown. ✅Leukocytosis 132.6 K/µL. Severe anemia (Hct 17%) with no regeneration (polychromatophils 11.5 K/µL). Profound thrombocytopenia: 15 K/µL. ✅Preliminary diagnosis based on blood smear morphology: acute lymphoid leukemia (ALL). Note the large number of mitoses. ✅Leukemic transformation of large cell lymphoma should, lege artis, be included in the differential diagnosis, but it is less likely here. ✅No piroplasmosis pathogens were found within the blood preparations. 👉This clinical case was kindly provided by - Olga Belozerova, clinical pathologist, head of the laboratory at the veterinary clinic “Noah’s Ark”, Kirov.