Oncohematology
Bone Marrow Examination: Modern ICSH Standards
Modern standards for bone marrow examination according to ICSH guidelines: aspirate morphology, trephine biopsy, flow cytometry, and genetic analysis.
Hemostasis
Revisiting the Critical Fibrinogen Threshold in Hypofibrinogenemia
A study suggests raising the critical fibrinogen level to 1.3 g/L. In acquired deficiency, this is an independent predictor of mortality.
Laboratory methods
Syllectometry: Analyzing Red Blood Cell Biomechanics and Aggregation
Principles of automated syllectometry for assessing red blood cell deformability and aggregation. Reference values and clinical significance of blood rheology.
Laboratory methods
Hematology Analyzer Comparability: A 4-Year Verification Study
A 4-year experience applying the CLSI EP31-A-IR protocol to verify the comparability of complete blood count results across nine hematology analyzers.
Hematology
Canine Blood Smear: Erythrocyte Agglutination in IMHA
Signs of severe erythrocyte autoagglutination in a canine blood smear with immune-mediated hemolytic anemia. Wright–Giemsa stain.
Hematology
Dual Red Blood Cell Population After Blood Transfusion
Blood smear in iron deficiency anemia after red blood cell transfusion: marked aniso-chromia, microcytosis, hypochromia, and increased RDW.
Parasitology
Diagnostic Features of Opisthorchis and Clonorchis Eggs
Key microscopic features of Opisthorchis and Clonorchis eggs: presence of an operculum with shoulders and a characteristic abopercular knob.
Parasitology
Neurocysticercosis: MRI and Taenia Solium Cyst Gross Specimen
Neurocysticercosis develops when Taenia solium larvae invade the CNS. Cystic lesion on brain MRI and gross photo of removed cysticerci.
Hematology
Gumprecht Shadow or Neutrophil Extracellular Trap: A Case
A practical hematology exercise: differential diagnosis of disintegrated leukocytes in a blood smear. Gumprecht shadow or neutrophil extracellular trap?
Oncohematology
Elongated Mature Lymphocytes in CLL Blood Smear
Morphology of elongated mature lymphocytes in a blood smear in chronic lymphocytic leukemia. Causes of spindle-shaped cell deformation and the influence of EDTA anticoagulant.
Parasitology
Parasitology Exercise: Identify the Ectoparasite Species
Parasitology test: identify the ectoparasite species from a macrophotograph of a female and operculated eggs on a hair. Clinical laboratory diagnostics.
Lab test interpretation
Protein Electrophoresis Case: Band Between Beta and Gamma
Clinical case study on serum protein electrophoresis: interpreting an additional fraction between beta- and gamma-globulins with total protein 72 g/L.