Oncohematology
Acute Lymphoblastic Leukemia B-IV: Morphology and Immunophenotyping
A case of B-IV acute lymphoblastic leukemia: blast morphology in bone marrow, myeloperoxidase cytochemistry, and immunophenotyping results.
Hematology
Toxic Granulation of Neutrophils: Morphology
Morphological features of toxic granulation in neutrophils on a blood smear: granule characteristics, staining, and diagnostic significance in inflammation.
Lab test interpretation
Sperm Agglutination and Aggregation in Spermogram
Types and degrees of sperm agglutination in spermogram. Distinguishing true agglutination from aggregation and its clinical significance in male infertility.
Oncohematology
Morphology of Lymphoid Cells in a Blood Smear
Morphological features of lymphoid cells: reactive lymphocytes, prolymphocytes, hairy cells, and lymphoblasts under microscopy.
Laboratory methods
Sperm Revitalization Solutions Test for Asthenozoospermia
Methodology for performing the sperm revitalization solutions test in asthenozoospermia: solution compositions, ejaculate mixing ratios, and kinesiogram calculation.
Lab test interpretation
Microscopy of Vaginal Smear: Reference Intervals
Reference values for microscopy of vaginal, cervical, and urethral discharge: normal ranges for leukocytes, epithelium, microflora, and criteria for pathological deviations.
Oncohematology
Acute Promyelocytic Leukemia: Promyelocyte Morphology
Morphological features of abnormal promyelocytes in acute promyelocytic leukemia (APL M3): butterfly-wing nuclei and marked hyperleukocytosis.
Lab test interpretation
Laboratory Diagnosis of Hyperthyroidism: An Algorithm
An algorithm for laboratory diagnosis of hyperthyroidism: evaluating TSH, free T4, T3, and anti-thyroid peroxidase antibodies for differential diagnosis.
Oncohematology
Bone Marrow Plasmacytes in Multiple Myeloma
Morphological features of plasmacytes in a myelogram in multiple myeloma: eccentric nucleus, basophilic cytoplasm, and perinuclear halo.
Hemostasis
Ticagrelor-Induced Thrombotic Thrombocytopenic Purpura
A case of ticagrelor-induced thrombotic thrombocytopenic purpura (TTP): microangiopathic hemolysis, schistocytosis in blood smear, and thrombocytopenia.
Hemostasis
Fibrin Formation and Fibrinolysis in Hemostasis
Mechanisms of fibrin formation and fibrinolysis: the role of thrombin, factor XIIIa, and the plasmin system in fibrin stabilization and complete clot formation.
Hematology
Electron Microscopy: Identify the Bone Marrow Cell
A diagnostic challenge in cell morphology: identify the hematopoietic bone marrow cell in this transmission electron micrograph (×13,000).