🔬Clinical case from a doctor from 🇮🇱Israel - Anna Belen. Suggest a diagnosis. The picture somewhat resembles the previous case of leukopenia, absence of granulocytic lineage. 16-year-old female patient, nasopharyngitis. Peripheral blood shows leukopenia, anemia: WBC 0.94; neutrophils 0.02, 2%; hemoglobin 111; platelets 204. Bone marrow aspirate in the photos. Immunophenotyping: blasts not detected, granulocytes absent. Histology: moderate bone marrow hypoplasia with severe myeloid hypoplasia and myeloid lineage maturation arrest. Increased number of plasma cells. Blasts not detected. Slight erythroid lineage proliferation. Megakaryocytes present, without significant proliferation.
Agranulocytosis: Myelogram in Granulopoiesis Reduction
A clinical case of severe neutropenia in a 16-year-old patient: bone marrow aspirate analysis, absence of granulocytes, and reactive plasmacytosis.
