Laboratory methods

Alpha-Naphthyl Acetate Esterase Activity in Monoblasts

Evaluating alpha-naphthyl acetate esterase activity in bone marrow smears to identify monocytic lineage cells: monoblast and promonocyte morphology.

Editorial team 1 min June 19, 2023

Bone marrow smear, alpha-naphthyl acetate esterase reaction in a monoblast

CYTOCHEMISTRY IN HEMATOLOGY. 🔬A cell with strong α-naphthyl acetate esterase activity from a normal bone marrow smear. 👉This cell has a slightly convoluted nucleus and a relatively small amount of cytoplasm and is most likely a monoblast or an early promonocyte.

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Artificial Intelligence in Bone Marrow Aspirate Analysis

Laboratory methods

Artificial Intelligence in Bone Marrow Aspirate Analysis

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Editorial team 2 min

Shubich Method: Granulocyte Cationic Protein Detection

Laboratory methods

Shubich Method: Granulocyte Cationic Protein Detection

The principle of Shubich's cytochemical reaction with bromophenol blue: detecting cationic lysosomal proteins as granules in the cytoplasm of blood neutrophils.

Иван Галак 1 min

Acute Lymphoblastic Leukemia: Morphology and Cytochemistry

Acute Lymphoblastic Leukemia: Morphology and Cytochemistry

A clinical case of acute lymphoblastic leukemia in a 21-year-old patient: blast morphology in blood and bone marrow, MPO, PAS, and lipid cytochemistry results.

Ekaterina Nozdrina 1 min