Anisocytosis and Poikilocytosis of Erythrocytes in Blood Smear

Anisocytosis and marked poikilocytosis of erythrocytes, dacryocytes, schistocytes, and giant platelets in the peripheral blood smear of a patient with severe anemia.

Nana Novikova 1 min February 27, 2026

Blood smear: marked anisopoikilocytosis of erythrocytes

Blood smear: ovalocytes, tear-drop cells, and platelets

Blood smear: giant platelet among poikilocytes

Analyzer printout: HGB 57 g/L, RBC 2.04×10¹²/L, PLT 591×10⁹/L

Blood smear: tear-drop erythrocyte (dacryocyte), indicated by arrow

Blood smear: deformed irregularly shaped schistocyte, arrow

Blood smear: ovalocyte in the field of view, indicated by arrow

Blood smear: fragmented erythrocyte with irregular contour, arrow

BEAUTIFUL ERYTHROCYTES. A 76-year-old female patient from the hematology department with severe anemia. In peripheral blood smears:

marked anisocytosis of erythrocytes (micro-, macrocytes),
marked poikilocytosis of erythrocytes (ovalocytes, echinocytes, stomatocytes, schistocytes, tear-drop cells, and what else?),
marked anisocytosis of platelets, giant platelet (photo 3).

🙏 The publication was kindly provided by KDL doctor Nana Novikova, CHUZ “KB” RZHD-Meditsina" Smolensk.

Read next

Severe Poikilocytosis in Complete Blood Count

Severe Poikilocytosis in Complete Blood Count

A clinical case of mild anemia: severe poikilocytosis, schistocytes, tear-drop cells, and macrothrombocytes in peripheral blood.

Nana Novikova 1 min

Poikilocytosis: Erythrocyte Morphology in Blood Smear

Poikilocytosis: Erythrocyte Morphology in Blood Smear

Erythrocyte morphology in severe poikilocytosis: detection of ovalocytes, dacryocytes, schistocytes, and stomatocytes in macrocytic anemia and cytopenia.

Nana Novikova 1 min

Dacryocytosis in Blood Smear with Oxidative Anemia

Dacryocytosis in Blood Smear with Oxidative Anemia

Morphology of tear-drop cells (dacryocytes) in a peripheral blood smear from a patient with oxidative anemia after splenectomy.

Editorial team 1 min