A female patient in the hematology department, diagnosed with lymphoma, presents with individual cells among mature lymphocytes in her peripheral blood, characterized by irregular nuclear shapes and uneven cytoplasmic contours (photos 1, 2). In the bone marrow aspirate (photos 4-9), there is an expansion of the lymphoid hematopoietic lineage – 34.7%. Of these, 6.0% are atypical lymphoid cells – large in size, with cord-like chromatin, and polymorphic nuclei (irregularly shaped, with indentations, split). Photo 9 shows an unusual, multinucleated lymphoid cell.
🙏 The publication was kindly provided by KDL physician Nana Novikova, CHUZ “KB” RZD-Meditsina" Smolensk.
