Morphological features of plasma cells in bone marrow in multiple myeloma: loss of perinuclear halo, multinucleated plasma cells.
Description of images The images show small and medium-sized plasma cells with loss of eccentric nuclear placement and the zone of arcoplasm. Nuclei with mature chromatin and cytoplasm with moderate basophilia (1) are observed, as well as plasma cells with two and three nuclei (2) (3).
Clinical information Patient diagnosed with multiple myeloma.
Sample type Bone marrow.
Staining type May-Grünwald-Giemsa.
Authors M. Abio, M. S. Toledo.
Workplace Hospital Virgen de la Salud, Toledo, Spain.
Morphology of plasma cells in bone marrow in multiple myeloma: 88% infiltration, atypical and binucleated plasma cell forms. Clinical case.
Evaluating bone marrow aspirate in multiple myeloma remission: mature plasma cell morphology, absence of atypia, and normal myelogram parameters.
A clinical case of multiple myeloma: bone marrow microscopy showing significant plasma cell infiltration and multinucleated atypical plasma cells.
