A clinical case of B12-deficiency anemia: hypersegmented neutrophils, anisopoikilocytosis, schistocytes, and oval macrocytes in peripheral blood.
Anemia, with pronounced poikilocytosis and anisocytosis, from microcytes and schistocytes to macrocytes and megalocytes. Hypersegmented neutrophils. What diagnosis would you suggest?
🙏 The publication was kindly provided by KDL physician Nana Novikova, CHUZ “KB” RZD-Meditsina, Smolensk.
A clinical review of pernicious anemia: severe B12 deficiency, pancytopenia, macrocytosis, critical LDH levels, and neurological symptoms.
What hypersegmentation of neutrophils in a blood smear means: diagnostic criteria, connection to B12 and folate deficiency, and granulocyte morphology.
Peripheral blood smear in vitamin B12 deficiency: severe macrocytosis with MCV 130 fL, megalocytes, poikilocytosis, and nucleated red blood cells.
