Basophilic Stippling of Erythrocytes in Blood Smear

What basophilic stippling of erythrocytes in a blood smear means: diagnostic significance in thalassemia, lead poisoning, and sideroblastic anemias.

Anna Feditskaya 1 min December 18, 2024

Blood smear, close-up: erythrocyte with pronounced basophilic stippling

Blood smear: erythrocyte with basophilic granulation among normocytes

Blood smear, overview field of view: single erythrocyte with basophilic stippling

🔬 Basophilic stippling of erythrocytes.
In adults, mild basophilic stippling has no specific diagnostic significance, similar to anisocytosis, and only indicates a non-specific reactive process. The detection of a large number of erythrocytes with basophilic stippling has diagnostic significance in thalassemia, lead poisoning, and sideroblastic anemia of any genesis.

🙏 Photos and description were kindly provided by biologist [Anna Feditskaya](https://vk.com/id147033613), Luhansk.