A 59-year-old female patient presents with leukopenia and anemia. This case study examines the morphology of large blasts with basophilic cytoplasm in the bone marrow during acute leukemia.
Hematology case study. A 59-year-old female patient. Peripheral blood shows leukopenia 1.26 ×10^9, 72% lymphocytes, normochromic normocytic anemia, Hb 80 g/L.
The photo shows hypercellular bone marrow. We note large blasts with abundant basophilic cytoplasm, and nuclei with prominent nucleoli. What morphological diagnosis can we assume?
🔬Case from the Head of the Morphology/IFT Department of A-Emek Medical Center Laboratory 🇮🇱Israel - Anna Belen.
A clinical case of untreated acute myelomonoblastic leukemia: 96% blasts in bone marrow, atypical mitoses, and severe pancytopenia.
Atypical blast forms in acute myeloid leukemia: Auer rods, hand-mirror cells, cup-like morphology, and flower-shaped nuclei in a blood smear.
Clinical case of MDS transforming to AML: 43% blasts, pronounced clasmatosis, signs of dyserythropoiesis, and cytochemical bone marrow results.
