Bone marrow cytochemistry in CMML: detection of monocytes and blasts using non-specific esterase reaction compared to Pappenheim staining.
👨🎨We are starting a cytochemistry week. 🔬Bone marrow of a patient with chronic myelomonocytic leukemia (CMML).
1 photo: Non-specific esterase reaction. Very large blasts and promonocytes are as strongly positive as normal-sized monocytes.
2 photo: Non-specific esterase reaction clearly differentiates monocytes, which can be difficult with Pappenheim staining.
3-4 photos in the carousel: bone marrow with Pappenheim staining.
✅Source: Löffler H. - Atlas of clinical hematology.5-ed, 2000
Criteria for differentiating monoblasts, promonocytes, and dysplastic monocytes in a blood smear in chronic myelomonocytic leukemia (CMML).
A case of B-IV acute lymphoblastic leukemia: blast morphology in bone marrow, myeloperoxidase cytochemistry, and immunophenotyping results.
A clinical case of CMML in a 73-year-old patient: absolute monocytosis, isolated blasts, dysgranulopoiesis, and neutrophil hyposegmentation in the blood smear.
