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Oncohematology

Diagnostic Challenge: Lymph Node Puncture Cytology

A clinical cytology challenge: differential diagnosis of atypical cells in a lymph node aspirate with suspected Hodgkin lymphoma.

Editorial team Editorial team 1 min
Lymph node aspirate smear, field of view with a large cell for differentiation
Lymph node aspirate smear, field of view with a large cell for differentiation
Cytological preparation of lymph node aspirate with polymorphic cells for the exercise
Cytological preparation of lymph node aspirate with polymorphic cells for the exercise
Lymph node aspirate smear, accumulation of cells of various sizes in the preparation
Lymph node aspirate smear, accumulation of cells of various sizes in the preparation
Cytological smear of lymph node aspirate, field of view for the diagnostic challenge
Cytological smear of lymph node aspirate, field of view for the diagnostic challenge
Lymph node aspirate preparation, cellular composition for diagnostic analysis
Lymph node aspirate preparation, cellular composition for diagnostic analysis
Lymph node aspirate smear, microphotography of a section of the preparation for the exercise
Lymph node aspirate smear, microphotography of a section of the preparation for the exercise
Cytological preparation of lymph node aspirate, microscopy of cellular composition
Cytological preparation of lymph node aspirate, microscopy of cellular composition
Lymph node aspirate smear, field of view with individual large cells
Lymph node aspirate smear, field of view with individual large cells
Cytological smear of lymph node aspirate, area with cells of different sizes
Cytological smear of lymph node aspirate, area with cells of different sizes
Lymph node aspirate preparation, microscope field of view for the clinical challenge
Lymph node aspirate preparation, microscope field of view for the clinical challenge

Anonymous question from a subscriber. Lymph node aspirate. Suspected Hodgkin lymphoma. Help with cell differentiation. Large blast-like cells, cells resembling epithelial cells, and cells with blue nucleoli are encountered. What do you think?

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