Leukoformula
RU EN
Oncohematology

Blast vs. Lymphoma Cells: Sysmex WPC Channel Insights

A clinical case demonstrating the differential diagnosis of blasts and atypical lymphocytes in suspected lymphoma using the WPC channel of a Sysmex XN-9100 analyzer.

Andrey Rudinsky Andrey Rudinsky 1 min
Digital blood smear, gallery of atypical mononuclears with a narrow rim of cytoplasm
Digital blood smear, gallery of atypical mononuclears with a narrow rim of cytoplasm
Digital blood smear, cells in the Blast (no lineage spec) category on the analyzer screen
Digital blood smear, cells in the Blast (no lineage spec) category on the analyzer screen
Digital smear analyzer screen, cell distribution by morphological classes
Digital smear analyzer screen, cell distribution by morphological classes
Digital microscope screen: differentiation of mature lymphocytes and atypical blasts
Digital microscope screen: differentiation of mature lymphocytes and atypical blasts
Sysmex XN-9100 analyzer screen, hemogram parameters and Abn Lympho? flag
Sysmex XN-9100 analyzer screen, hemogram parameters and Abn Lympho? flag
Sysmex analyzer WPC channel scattergram with atypical lymphocyte and blast zones
Sysmex analyzer WPC channel scattergram with atypical lymphocyte and blast zones
Sysmex analyzer WDF, WNR, and WPC scattergrams with atypical cell gate markings
Sysmex analyzer WDF, WNR, and WPC scattergrams with atypical cell gate markings
Diagram from the user manual: differentiation of lymphocytes and blasts in the WPC channel
Diagram from the user manual: differentiation of lymphocytes and blasts in the WPC channel

A 70-year-old woman. Blasts or atypical lymphocytes – lymphoma cells? The WPC channel of the Sysmex XN 9100 hematology analyzer suggests the origin of the cells. 🙏 Material kindly provided by clinical laboratory diagnostics physician Andrey Rudinsky, Hadassah Medical Moscow.

Read next

100%