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Oncohematology

Differential Diagnosis of Blasts in Blood Smears

Criteria for morphological differentiation of blast cells, lymphocytes, and megakaryocyte nuclear fragments in peripheral blood smears under microscopy.

Anna Belen Anna Belen 1 min
Blood smear: blast cell with delicate chromatin and a narrow rim of cytoplasm
Blood smear: blast cell with delicate chromatin and a narrow rim of cytoplasm
Blood smear: blast with polymorphic nucleus and basophilic cytoplasm
Blood smear: blast with polymorphic nucleus and basophilic cytoplasm
Blood smear: mature lymphocyte with dense clumpy chromatin structure
Blood smear: mature lymphocyte with dense clumpy chromatin structure
Blood smear: denuded megakaryocyte nuclear fragment with hyperchromatic structure
Blood smear: denuded megakaryocyte nuclear fragment with hyperchromatic structure
Blood smear: blast cell with cytoplasmic protrusion and nucleolus
Blood smear: blast cell with cytoplasmic protrusion and nucleolus
Blood smear: angular blast with a light nucleolus in the nucleus
Blood smear: angular blast with a light nucleolus in the nucleus
Blood smear: small lymphocyte with compact nucleus and light cytoplasm
Blood smear: small lymphocyte with compact nucleus and light cytoplasm
Blood smear: flattened, elongated blast with delicate chromatin
Blood smear: flattened, elongated blast with delicate chromatin
Blood smear: round blast cell with signs of nucleolar apparatus
Blood smear: round blast cell with signs of nucleolar apparatus

‼Correct answer to the challenge from the closed club of laboratory hematologists. ✅Blasts: 1,2,5,6,8,9; ⚠ Lymphocytes: 3,7; ⚠ Megakaryocyte nuclear fragment: 4.

✅ The first 7 correct respondents: Natalia Goncharova Tatyana Novikova Inga Prokofyeva Yulia Tretyakova Olga Slatvinskaya Oksana Petrovskaya Deleted Deleted 🎊Congratulations to the winners! Private invitations to join the closed club have been sent to personal messages.

Special thanks to the Head of the Morphology/IFT Department of Ha-Emek Medical Center Laboratory, Afula 🇮🇱Israel - Anna Belen for providing materials for the challenge!

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