Features of granulocytopoiesis: why promyelocytes do not differentiate by cell lines and at what stage of granulocyte maturation specific granules appear.
At the promyelocyte stage, it is not yet possible to distinguish between a basophil, neutrophil, and eosinophil, as the granules in the cytoplasm at this stage are non-specific (azurophilic).
At the myelocyte stage, specific granules characteristic of a certain type of leukocyte begin to appear:
For neutrophils — neutrophilic granules. For eosinophils — eosinophilic granules. For basophils — basophilic granules.
Morphological features of promyelocytes: nucleo-cytoplasmic ratio, azurophilic granules, Golgi zone, and identification criteria in blood smears.
Explore the morphological features of eosinophilic myelocytes: nuclear structure, Golgi zone, and the ratio of immature proeosinophilic to mature orange granules.
Explore the morphological features of myelocytes in blood smears: chromatin structure without nucleoli, specific cytoplasmic granulation, and differential diagnosis.
