Platelet Dysplasia Mimicking Trypanosomiasis

A case of severe platelet dysplasia in a 66-year-old patient. Morphology of atypical platelets in blood smear, analyzer histograms, and resemblance to trypanosomiasis.

Alena Azarenkova 1 min July 7, 2025

Blood smear: dysplastic spindle-shaped platelet with a cytoplasmic outgrowth

Blood smear: crescent-shaped platelet mimicking a parasite, and marked anisocytosis

Blood smear: platelet anisocytosis with micro- and macroforms present in the field of view

Blood smear: sharply elongated platelet among red blood cells of various sizes

Blood smear: marked polymorphism and dysplasia of blood platelets

Blood smear: elongated platelet with granules, resembling the shape of a trypanosome

Blood smear: platelet with a thin appendage, mimicking a protozoan flagellum

Analyzer printout: abnormal PLT histogram and diagnostic scattergrams

🔬 Severe platelet dysplasia in a 66-year-old man, mimicking trypanosomiasis!

✅ Blood smear microscopy images and hematology analyzer scattergrams. 🙏 The publication was kindly provided by clinical laboratory diagnostics physician Alena Azarenkova

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