Laboratory methods
Quality Control Failure on a Biochemical Analyzer: A Case
A clinical laboratory quality control case: consistently low bilirubin on a biochemical photometer while other tests are normal. Determine the cause of the failure.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Laboratory methods
Photometer Lamp Defect: Causes of Underestimated Bilirubin
Why a biochemical analyzer lamp defect distorts bilirubin levels: features of photometry, spectral range, and diagnosis of hardware errors.
Hematology
3D Reconstruction of Erythrocyte Morphology by ODT
Application of optical diffraction tomography (ODT) for 3D visualization of live erythrocytes and poikilocytes without fixation and staining.
Parasitology
Morphology of Helminth Eggs: Schistosoma, Enterobius, Moniezia
Microscopic features of parasite eggs: Schistosoma mansoni, Enterobius vermicularis, Moniezia benedeni, and Moniezia expansa in native preparations.
Oncohematology
Multiple Myeloma with Normal CBC and Urinalysis Results
A clinical case of multiple myeloma: normal CBC and urinalysis, hyperproteinemia, M-gradient on electrophoresis, and bone marrow plasmacytosis.
Laboratory methods
Light Microscopy in Clinical Laboratory Hematology
A day in the life of a clinical laboratory doctor: a lilac flower on a microscope slide. Unusual findings in the clinical diagnostic laboratory.
Hematology
Critical Normoblastosis in Severe Microcytic Anemia
A case of severe microcytic anemia with normoblastosis (864/100 WBC): erythrocyte morphology, target cells, Howell-Jolly bodies, and analyzer scattergram.
Laboratory methods
Sysmex XN Analyzer for Effusion Fluid Analysis
Capabilities of the Sysmex XN analyzer in pleural and ascitic fluid analysis. Significance of the HF-BF parameter and the necessity of microscopy in tumors.
Lab test interpretation
Coproscopy Exercise: Round Formations in Stool Samples
A diagnostic exercise in stool microscopy. Evaluate native smear, as well as samples with Sudan III and Lugol's solution for structure identification.
Laboratory methods
Cytological Criteria for Malignancy in Tumors
Key cytological criteria of malignancy: anisocytosis, anisokaryosis, atypical mitoses, nuclear polymorphism, and cell cannibalism in microscopy.
Parasitology
Microscopy of Giardia Cysts and Opisthorchis Eggs
Microscopic view of parasites under immersion: Lamblia intestinalis (Giardia) cysts and Opisthorchis felineus fluke egg. Essential for laboratory diagnostics.
Hematology
Osteoclast Morphology in Bone Marrow Aspirate
Morphological features of an osteoclast in a normal bone marrow aspirate: granular cytoplasm, multiple homogeneous nuclei with single nucleoli.