Oncohematology
Myeloblast Morphology in Peripheral Blood Smear
Morphological features of myeloblasts: nucleus structure, nucleoli, cytoplasmic granules, and the necessity of immunophenotyping for differential diagnosis.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Lab test interpretation
Microscopy Challenge: Unusual Structure in Rhinocytogram
A clinical microscopy challenge from a nasal smear: identify the nature of a suspicious structure found during rhinocytogram analysis.
Lab test interpretation
Uric Acid Crystals in Complete Urinalysis: Microscopy
Microscopy of urine sediment in pronounced crystalluria: morphology of large uric acid crystals, visible to the naked eye on a microscope slide.
Parasitology
Lamblia intestinalis Cysts in a Stool Smear
Morphology of Lamblia intestinalis cysts in the stool of a 4-year-old child. Microscopy of a native preparation with Lugol's solution at x400 magnification for giardiasis diagnosis.
Parasitology
Identifying Trichomonads in Smear Microscopy
Features of detecting Trichomonas vaginalis in smear microscopy: differential diagnosis with leukocytes amidst pronounced inflammation.
Oncohematology
Blood Picture in Osteomyelofibrosis: A Clinical Case
A clinical case of osteomyelofibrosis in a 72-year-old female patient with marked leukocytosis, a left shift of the leukocyte differential to myelocytes, and anemia.
Lab test interpretation
Multinucleated Giant Cells in Soft Tissue Cytology
Morphology of multinucleated giant cells in bone and soft tissue cytological preparations: cytoplasm, nuclei, and differential diagnosis with osteoclasts.
Oncohematology
Hemorrhagic Syndrome in Multiple Myeloma: Clinical Manifestations
Explore the clinical manifestations of multiple myeloma, focusing on hemorrhagic syndrome and mucosal bleeding in the oral cavity associated with plasma cell tumors.
Hematology
Proerythroblast Morphology in Bone Marrow Smears
Key morphological features of proerythroblasts in bone marrow aspirates: intense cytoplasmic basophilia, ear-like protrusions, and fine chromatin structure.
Parasitology
Stool Microscopy: Searching for Protozoa in Acute Diarrhea
Clinical case and stool microscopy in an 18-year-old male with fever and diarrhea. Evaluation of native smear, Romanowsky stain, and Lugol's solution preparation.
Laboratory methods
Chorionic Villus Sampling for Karyotyping: Preparation
Steps for preparing chorionic villus cells for karyotyping: hypotonia, colchicine treatment, mechanical cytolysis, and metaphase plate staining.
Lab test interpretation
Amyloid Bodies in Post-Massage Urine: Microscopy
Morphology and microscopy of amyloid bodies in post-massage urine sediment. Features of detecting layered formations during prostate secretion microscopy.