
Bacteria and Fungi in Blood Smears: Sepsis or Artifact?
How to distinguish true bacteremia in sepsis from blood smear contamination and staining artifacts. Analysis of microscopic findings and fungal spores.
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.

How to distinguish true bacteremia in sepsis from blood smear contamination and staining artifacts. Analysis of microscopic findings and fungal spores.

Cytological features of bone marrow aspirate: large erythroblastic island, binucleated normoblasts, and pronounced megakaryocyte polymorphism.

Clinical case of galactosemia in an 8-month-old infant: GALT enzyme deficiency, bone marrow cell vacuolization, intoxication symptoms, and early cataracts.

Cytological examination of a canine external ear canal smear: morphology of budding yeast-like fungi Malassezia spp. and anucleated epithelium.

Explore the morphological features of plasmacytoid lymphocytes in blood smears and their characteristic appearance on hematology analyzer scattergrams.

Features of acute lymphoblastic leukemia in infants: KMT2A gene mutations, blast morphology in bone marrow, and PAS and MPO reactions.

Cytological picture of bone marrow aspirate in anemia: erythroid and megakaryocytic hyperplasia, emperipolesis, and binucleated normoblasts.

Microscopy of urine sediment in cystinuria: visualization of pathological hexagonal cystine crystals in a native preparation. An example from veterinary practice.

A 67-year-old patient with polycythemia vera: Sysmex analyzer parameters, blast flags, anemia, and bone marrow aspirate cytology are presented in this clinical case.

Morphological features of proerythroblasts (pronormoblasts): size, cytoplasmic basophilia, chromatin structure, and differentiation in bone marrow.

Morphological diagnosis of Plasmodium falciparum tropical malaria: ring-form trophozoites, schizonts, and gametocytes in a peripheral blood smear.

Morphological features of lymphoid cells with split nuclei in peripheral blood in a lymphoma patient: criteria for microscopic evaluation.