
Granulocyte Hypersegmentation in Hydroxyurea Therapy
Clinical case: hypersegmentation of neutrophil, eosinophil, and basophil nuclei in a blood smear during hydroxyurea treatment for polycythemia vera.
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.

Clinical case: hypersegmentation of neutrophil, eosinophil, and basophil nuclei in a blood smear during hydroxyurea treatment for polycythemia vera.

Explore the forms, pathogenesis, and diagnosis of extramedullary disease in multiple myeloma, including clonal migration mechanisms, imaging, and therapeutic approaches.

A clinical case of malaria after travel to Uganda: identification of Plasmodium falciparum ring forms in a blood smear, differential diagnosis, and PCR confirmation.

Microscopy of a blood smear showing platelet aggregation, fibrin strands, and toxic granulation of neutrophils in severe leukocytosis and thrombocytosis.

Microscopic detection of Capillaria nematode larvae in urine sediment. Features of laboratory diagnosis of urogenital capillariasis in animals.

Learn about the hook effect in laboratory diagnostics, how it impacts biochemical test results, and strategies to avoid it for accurate interpretation.

What are cold agglutinins, how do they cause red blood cell clumping, and how to eliminate agglutination by warming a blood tube to 37°C in the lab.

A diagnostic exercise in blood smear microscopy. Identify altered cells in a patient with hepatomegaly and jaundice. Erythrocyte morphology test.

Laboratory signs of chylothorax in cats: macroscopic appearance of chyle, effusion cytology with lymphocyte predominance, and main causes of the pathology.

Morphological features of bone marrow in thrombocytosis: megakaryocytic hyperplasia and active platelet budding in aspirate.

Morphological variants of Berezovsky-Sternberg cells: popcorn cells and coins on a saucer in the cytological diagnosis of Hodgkin lymphoma.

Microscopic blood smear findings in hemoglobinopathy D. Identification of target cells and specific red blood cell morphology.