Hematology
Cell Nucleus Chromatin Patterns: Descriptive Terminology
How to describe chromatin structure in the cell nucleus: English classification of patterns and terminology options in Russian laboratory practice.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Hematology
Differential Diagnosis of Iron Deficiency and B12 Anemia
A clinical case review: differentiating microcytic iron deficiency anemia and vitamin B12 deficiency based on MCV and ferritin levels.
Laboratory methods
DNA Molecule Structure: Fundamentals of Molecular Genetics
Features of DNA double helix structure, principles of genetic material organization, and molecular diagnostic methods in the clinical laboratory.
Oncohematology
Blood Smear Morphology in Primary Myelofibrosis
Peripheral blood smear findings in primary myelofibrosis: leucoerythroblastosis, dacryocytes, micromegakaryocytes, and giant platelets on microscopy.
Laboratory methods
Romanowsky Staining of Blood Smears: Method History
The history of polychromatic blood smear staining: contributions of D. L. Romanowsky and Ch. I. Khentsinsky, mechanism, and ICSH recognition.
Hematology
Neutrophil Phagocytosis of Bacteria in Bacteremia
A clinical case of bacteremia: detection of rod-shaped bacteria phagocytosed by neutrophils during digital microscopy of a peripheral blood smear.
Lab test interpretation
Critical Hypoglycemia & Errors in Biochemistry Reports
We discuss critical blood glucose levels, the consequences of severe hypoglycemia, and post-analytical errors in biochemical analysis reports.
Lab test interpretation
Vitamin D-Deficient Rickets in an Adolescent: A Clinical Case
A clinical case of vitamin D-deficient rickets in an adolescent misdiagnosed as arthritis: 25(OH)D, parathyroid hormone, and alkaline phosphatase in diagnosis.
Hematology
Counting Band Neutrophils in Blood Smears: Why It Matters
Why determine band neutrophils in the leukocyte formula: diagnosis of sepsis and SIRS, the link between band shift and mortality risk.
Parasitology
Tapeworm Diagnosis in Stool: A Clinical Case
A clinical case of a rare tapeworm identified by microscopy of a native stool sample in a child with chronic diarrhea and anemia.
Hematology
Drug-Induced Immune Hemolytic Anemia: Medications
A table of medications causing immune hemolytic anemia and the importance of collecting a pharmacological history when the direct Coombs test is positive.
Hematology
Blood Group Determination on the Shroud of Turin
Laboratory findings on blood traces from the Shroud of Turin: hemoglobin detection, determination of blood group AB (IV), and DNA analysis.