Oncohematology
Bone Marrow Examination: Modern ICSH Standards
Modern standards for bone marrow examination according to ICSH guidelines: aspirate morphology, trephine biopsy, flow cytometry, and genetic analysis.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Hematology
Megakaryocyte Morphology and Emperipolesis in Bone Marrow
Normal megakaryocyte morphology in bone marrow: multilobed nucleus, signs of emperipolesis in the cytoplasm, and platelet formation.
Hematology
Primary Hemochromatosis: Types and Lab Diagnostics
Comparative table of phenotypic variants of primary hemochromatosis: types 1–4, age of manifestation, ferritin level, and transferrin saturation.
Hematology
Endothelial Cells in Blood Smear vs. Hairy Cell Leukemia
Morphological differences between endothelial cells and hairy cell leukemia cells in peripheral blood smear: chromatin and cytoplasm features.
Hematology
Morphological Signs of Dyserythropoiesis in Bone Marrow
Dyserythropoiesis in bone marrow aspirate: morphology of erythroid precursors, nuclear deformation, multinuclearity, and megaloblastoid cell changes.
Parasitology
Malarial Plasmodium Gametocytes in a Blood Smear
Detection of Plasmodium gametocytes in a peripheral blood smear one day after schizonts were found. Laboratory diagnosis of malaria.
Hematology
Gaucher Cells in Pediatric Bone Marrow Aspirate
Morphology of atypical macrophages (Gaucher cells) in a child's bone marrow. Diagnosis of Gaucher disease: enzymatic analysis and GBA gene sequencing.
Hematology
Elliptocyte Morphology in Peripheral Blood Smears
How to distinguish true elliptocytes in a blood smear from preparation artifacts: cell orientation features and microscopic evaluation criteria.
Hematology
Osteoblasts in Bone Marrow Aspirate: Morphology
Morphological features and differential diagnosis of osteoblast clusters in bone marrow smears stained with May-Grünwald-Giemsa.
Hematology
Hypersegmented Neutrophils in a Blood Smear
What hypersegmentation of neutrophils in a blood smear means: diagnostic criteria, connection to B12 and folate deficiency, and granulocyte morphology.
Oncohematology
Rouleaux Formation in Multiple Myeloma
The phenomenon of rouleaux formation in a peripheral blood smear in multiple myeloma with high IgG levels. A case study from Madrid.
Hematology
Osteoblasts in Bone Marrow Aspirate: Morphology
Morphological features of osteoblasts in bone marrow aspirate: eccentric nucleus, perinuclear zone, and differential diagnosis with carcinoma cells.