Oncohematology
Hematology Case: Retinal Vein Occlusion and Paraprotein
Clinical case: A 69-year-old patient presents with retinal vein occlusion, lymphadenopathy, IgM paraprotein, and bone marrow changes. Determine the diagnosis.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Oncohematology
Blasts in a Child's Blood Smear: Leukocytosis and Cytopenia
Clinical case of a 2-year-old child: leukocytosis 45.7×10⁹/L, anemia, thrombocytopenia. Differential diagnosis of blast cells in a blood smear.
Hematology
Clinical Symptoms of Anemia: Missing Signs
Exploring the clinical manifestations and symptoms of anemic syndrome: identifying signs of hypoxia and sideropenia not included in the provided diagram.
Oncohematology
Blast Morphology in Peripheral Blood Smear
Clinical case review: differential diagnosis of binucleated blasts and large granular lymphocytes in a peripheral blood smear from a 68-year-old woman.
Hematology
Sysmex AS-LYMP Parameter in COVID-19 Patients
Reduced levels of antibody-synthesizing lymphocytes (AS-LYMP) on Sysmex XN analyzers in COVID-19 as an early marker of severity and predictor of fatal outcome.
Oncohematology
Botkin-Gumprecht Shadows in Chronic Lymphocytic Leukemia
What are Botkin-Gumprecht shadows, their formation mechanism during blood smear preparation, and their diagnostic significance in chronic lymphocytic leukemia.
Oncohematology
Acute Leukemia: 48% Blasts in Peripheral Blood
A 90-year-old female patient's complete blood count: leukocytosis 22.7×10⁹/L, thrombocytopenia, severe anemia, and 48% blast cells in the peripheral blood smear.
Oncohematology
Blastemia in Peripheral Blood in Acute Leukemia
Clinical case of blastemia in a 90-year-old female patient: leukocytosis 81.9×10⁹/L, 35% blasts in peripheral blood, and cell morphology with Romanowsky stain.
Laboratory methods
Lipemia in CBC: False MCHC and Plasma Replacement
How lipemia (chylosis) inflates hemoglobin and MCHC levels in a complete blood count. A method for correcting results using plasma replacement with saline solution.
Parasitology
Microfilariae Suspicion vs. Artifacts in Blood Smear
Unusual spiral inclusion in a peripheral blood smear: differential diagnosis of microfilariae and laboratory artifacts in light microscopy.
Hematology
Morphological Differences: Pronormoblast vs. Promyelocyte
Comparative morphology of pronormoblast and promyelocyte: nuclear structure, chromatin, and cytoplasm features in blood smear microscopy.
Hematology
Identifying Basophils in Peripheral Blood Smears
Learn to identify basophils in peripheral blood smears: characteristic granulation, nuclear shape, and differential diagnosis from other leukocytes.