Oncohematology
Morphological Identification of Blasts in Blood Smear
Tips for recognizing blasts in a blood smear: evaluate chromatin structure compared to erythroblasts, population monotony, and cell arrangement.
Articles
Blood and bone marrow morphology, clinical cases and diagnostic algorithms. Most of the library is in Russian; the English section is growing.
Most of our material is written in Russian — that is the working language of the community. A few pieces exist in English; the rest of the library is one click away and the photographs need no translation.
Hematology
Morphology Challenge: Classifying Blood Cells in a Smear
A clinical case study on blood smear microscopy: classify two nucleated cells by assessing chromatin and cytoplasm structure. Test your diagnostic skills.
Oncohematology
Hairy Cell Leukemia: Blood Picture and Cell Morphology
A clinical case of hairy cell leukemia: leukocytosis up to 99.6×10⁹/L, morphology of hairy cells in a blood smear, and analyzer scattergram.
Hematology
Bacteria in Blood Smear in Sepsis: Klebsiella pneumoniae
Clinical case of Klebsiella pneumoniae bacteremia in sepsis during COVID-19: morphology of bacteria in blood smear and complete blood count dynamics.
Oncohematology
Adult T-Cell Lymphoma: Flower Cells in Blood Smear
Morphology of lymphocytes with multi-lobed nuclei (flower cells) in adult T-cell leukemia/lymphoma (ATLL). Peripheral blood smear microscopy.
Oncohematology
Chronic Lymphocytic Leukemia: Blood Count & Smear
Clinical case of a 67-year-old female patient with leukocytosis (111×10⁹/L): morphology of mature lymphocytes and Botkin-Gumprecht shadows, suspecting CLL.
Oncohematology
Bone Marrow Metastasis: Cytological Picture
A clinical case of solid tumor metastasis to the bone marrow in a patient suspected of acute hemoblastosis: myelogram analysis and cell morphology.
Lab test interpretation
Alkaline Phosphatase in Liver Injury: An Assessment Algorithm
Causes of elevated alkaline phosphatase in hepatitis, cholestasis, and liver tumors. Differential diagnosis algorithm based on enzyme elevation levels.
Oncohematology
Cellular Cannibalism: Entosis in Cytological Diagnosis
What are cellular cannibalism and entosis in malignant tumors: biological mechanisms, cytological signs, and clinical significance of the phenomenon.
Hematology
Folic Acid Deficiency and Anemia During Lactation
A clinical case review of anemia due to folic acid and vitamin D deficiency in a breastfeeding woman. Evaluation of complete blood count and biochemistry.
Oncohematology
Langerhans Cell Histiocytosis in Bone Marrow
Morphology of Langerhans cells in bone marrow aspirate, clinical manifestations, immunophenotype (CD1a, langerin), and diagnostic criteria for histiocytosis.
Hematology
Severe Iron Deficiency Anemia with Hemoglobin 18 g/L
A clinical case of critical iron deficiency anemia: hematological parameters, erythrocyte morphology in a blood smear, and biochemical markers.