Hematology

Echinocytes in Blood Smear with Pyruvate Kinase Deficiency

Erythrocyte morphology in pyruvate kinase deficiency: numerous echinocytes with spicules appear in the peripheral blood smear.

Blood smear: echinocytes with characteristic spicules and a segmented neutrophil
Blood smear: echinocytes with characteristic spicules and a segmented neutrophil

🩸3D-erythrocytes. 🔬Pyruvate Kinase Deficiency.

✅A large number of echinocytes can be seen in the blood smear. In pyruvate kinase deficiency, it is typical to observe a large number of echinocytes, which are erythrocytes with small spicules uniformly distributed over the entire surface, giving the cell a three-dimensional appearance.

✅Source: Clinical Hospital University Virgen de la Arrixaca, Murcia, Spain. Mercedes Berenguer Piqueras.