Endothelial Cells in Blood Smear vs. Hairy Cell Leukemia

Morphological differences between endothelial cells and hairy cell leukemia cells in peripheral blood smear: chromatin and cytoplasm features.

Editorial team 1 min September 26, 2026

Blood smear: endothelial cells with processes in the cytoplasm

Sometimes endothelial cells in an image look very similar to hairy cell leukemia cells, but the chromatin structure is significantly different.

🔬 Source: from the archive of Brazilian hematology specialist Marcio Melo

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