Hematology

Evans Syndrome: Hemolytic Anemia Blood Smear Morphology

Blood smear morphology in Evans Syndrome: severe hemolysis, polychromasia, basophilic stippling, Howell-Jolly bodies, and normoblasts in peripheral blood.

Evans Syndrome in a 34-year-old patient. In this case, hemolytic anemia develops. Platelets are even reactively elevated. Signs of hemolysis are noted: hemoglobin Hb 64 g/l, LDH increased 2-fold, total and direct bilirubin 3-fold, haptoglobin sharply decreased, reticulocytes 12.5%, leucoerythroblastosis in peripheral blood, and corresponding morphology (images below).

🔬The case was kindly shared by the Head of the Morphology/IFT Department of the Ha-Emek Medical Center Laboratory, Afula 🇮🇱Israel - Anna Belen.