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Oncohematology

Giant Megakaryocytes in Bone Marrow with Thrombocytosis

Morphology of giant megakaryocytes in bone marrow aspirate and blood smear in a 57-year-old female patient with severe thrombocytosis (897×10⁹/L).

Nana Novikova Nana Novikova 1 min
Bone marrow smear: giant mature megakaryocyte with abundant cytoplasm
Bone marrow smear: giant mature megakaryocyte with abundant cytoplasm
Bone marrow smear: megakaryocyte with pronounced hyperlobulated nucleus
Bone marrow smear: megakaryocyte with pronounced hyperlobulated nucleus
Bone marrow smear: megakaryocyte amidst erythroid and granulocytopoietic cells
Bone marrow smear: megakaryocyte amidst erythroid and granulocytopoietic cells
Bone marrow smear: two giant megakaryocytes with polyploid nuclei
Bone marrow smear: two giant megakaryocytes with polyploid nuclei
Bone marrow smear: megakaryocyte surrounded by myeloid progenitor cells
Bone marrow smear: megakaryocyte surrounded by myeloid progenitor cells
Bone marrow smear: mature megakaryocyte with hypersegmented nucleus
Bone marrow smear: mature megakaryocyte with hypersegmented nucleus
Analyzer printout: platelet count 897×10^9/L and leukocyte count 10.04×10^9/L
Analyzer printout: platelet count 897×10^9/L and leukocyte count 10.04×10^9/L
Blood smear: platelet clumps, band and segmented neutrophils
Blood smear: platelet clumps, band and segmented neutrophils
Blood smear: pronounced thrombocythemia in fields of view, mature granulocytes
Blood smear: pronounced thrombocythemia in fields of view, mature granulocytes

GIANT MEGAKARYOCYTES in bone marrow aspirate from a 57-year-old female patient examined for THROMBOCYTOSIS (PLT 897×10^9/L). Peripheral blood (photos 8,9).

🙏 The publication was kindly provided by KDL physician Nana Novikova, CHUZ “KB” RZD-Meditsina, Smolensk.

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