A clinical case of severe vitamin B12, folic acid, and iron deficiency: giant cells with hypersegmented nuclei in a bone marrow smear.
Bone marrow with the presence of very large cells and pronounced hypersegmentation
Clinical information A 2-year-old girl with severe malnutrition and a history of acute B-cell lymphoblastic leukemia
Biological information Severe deficiency of all maturation factors (vitamin B12, folic acid, and iron)
Sample type Bone marrow
Staining type May-Grünwald-Giemsa
Authors Sarrate García, Edurne; Casanova Galán, Evelyn
Workplace Hospital Sant Joan de Déu, Barcelona, Spain
Morphological signs of dysgranulocytopoiesis and dyserythropoiesis in bone marrow aspirate in severe B12-deficiency anemia: a clinical case.
A clinical case of severe vitamin B12 deficiency with pancytopenia: blue bone marrow morphology and differential diagnostic errors.
Morphology of a giant, degeneratively altered neutrophil in bone marrow aspirate: nuclear and cytoplasmic features, and diagnostic significance.
