🔬 Neutrophil Hypersegmentation in a Blood Smear A 72-year-old woman was admitted with acute bronchitis. History: essential (hemorrhagic) thrombocythemia. 🩸 CBC Results: ✅ Leukocytes (WBC): 16.27 × 10⁹/L (normal 4.0 – 9.0 × 10⁹/L) – leukocytosis here likely indicates acute inflammation. ✅ Erythrocytes (RBC): 2.88 × 10¹²/L (normal 3.5 – 5.5 × 10¹²/L) – low values, possible signs of anemia. ✅ Hemoglobin (HGB): 115 g/L (normal 120 – 160 g/L) – anemia ✅ MCV: 119.10 fL – macrocytic anemia ✅ Platelets (PLT): 805 × 10⁹/L (normal 150 – 400 × 10⁹/L) – thrombocytosis, confirming the diagnosis of essential thrombocythemia. ✅ Neutrophils (NEUT#): 14.49 × 10⁹/L (normal 2.0 – 7.5 × 10⁹/L) – elevated count, characteristic of bacterial infection. ✅ ESR: 60 mm/h (normal 2 – 20 mm/h) – indicates the presence of an inflammatory process. MCV 119.10 📊 Interpretation: This picture is typical for an infectious-inflammatory process complicating the patient’s chronic blood disorder. Such a case requires careful monitoring and a comprehensive approach to treatment, considering both the underlying disease and the concomitant infection.
❓What are the causes of hypersegmentation, colleagues? Please offer your interpretation of the study results.
🙏 Clinical case kindly provided by laboratory physician Maria Bozhok, Vladivostok.
