Naked Megakaryocyte Nuclei in Peripheral Blood Smear

❗Naked megakaryocyte nuclei in the blood smear of a 70-year-old woman.

✅ Diagnoses indicated in the referral: Primary myelofibrosis? Essential thrombocythemia?

🩸 Complete Blood Count: WBC - 16.9 * 10^{9/L Absolute Neutrophils - 11.06 * 10}9/L Neutrophils % - 65.5% Absolute Monocytes - 2.48 * 10^{9/L Monocytes % - 14.7% Hemoglobin - 108 g/L Hematocrit - 33.9% MCH - 25.5 pg MCHC - 317 g/L Platelets - 1057 * 10}9/L

🔬 Differential Leukocyte Count: Blasts - 3% Myelocytes - 10% Metamyelocytes - 9% Normoblasts - 10 per 100 leukocytes Giant platelets Naked megakaryocyte nuclei (indicated by arrows)

🙏The clinical case was kindly provided by Clinical Laboratory Diagnostics physician Maria Bozhok↗, Vladivostok