Morphology of plasma cells with needle-shaped cytoplasmic inclusions of immunoglobulin crystals in monoclonal gammopathies.
Plasma cell with needle-shaped inclusions
Authors: Gloria Pérez Segura, Sandra Gómez Rojas, Gabriela
Source: GECH Atlas 2026
Description: The image shows a plasma cell containing specific needle-shaped cytoplasmic inclusions. Such morphological changes can be observed in various lymphoproliferative diseases and monoclonal gammopathies. The inclusions represent accumulations of immunoglobulins crystallized within the cell.
Morphological features of plasma cells in bone marrow in multiple myeloma: loss of perinuclear halo, multinucleated plasma cells.
Clinical case of multiple myeloma: an atypical plasma cell with crystalline needle-like inclusions in a bone marrow smear.
Cytological features of multiple myeloma in bone marrow aspirate: atypical plasma cells with multi-lobed, flower-shaped nuclei.
