Blood Picture in Osteomyelofibrosis: A Clinical Case

A clinical case of osteomyelofibrosis in a 72-year-old female patient with marked leukocytosis, a left shift of the leukocyte differential to myelocytes, and anemia.

Anonimnyy Avtor 1 min July 30, 2025

Blood smear: accumulation of granulocytes at different stages of maturation and myelocytes

Blood smear: myelocyte, segmented neutrophil, and anisocytosis of erythrocytes

Blood smear: pronounced left shift of the leukocyte differential with predominance of myelocytes

Blood smear: immature granulocytes and single blasts in the field of view

Blood smear: group of intermediate forms of granulocytic maturation

Blood smear: myelocytes and normoblast against a background of pronounced poikilocytosis

Blood smear: myelocytes, metamyelocyte, and disrupted leukocyte forms

A 72-year-old woman, blood sample brought from the therapeutic department with a diagnosis of iron deficiency anemia. Leukocytosis 136.9 * 10^9/L Platelets 99 Erythrocytes 2.81 Hemoglobin 80 ESR 13 Blasts 2%, myelocytes 54%, increased basophils. Referred for consultation with a hematologist, final diagnosis after myelogram and immunophenotyping - osteomyelofibrosis. Anonymous, please ☺️