A diagnostic challenge in bone marrow biopsy microscopy for a patient with multiple myeloma. Identify the cells indicated by arrows in the specimen.
💡 An exercise from the closed club of laboratory hematologists. The following cells (indicated by arrows) were found during microscopy of a bone marrow biopsy from a patient with multiple myeloma. ❓ What do you think these cells are?
The first 3 people who answer correctly in the comments will receive an invitation to the closed club. THE CORRECT ANSWER IS TOMORROW!
Cytological features of multiple myeloma in bone marrow aspirate: atypical plasma cells with multi-lobed, flower-shaped nuclei.
Morphological features of plasma cells in bone marrow in multiple myeloma: loss of perinuclear halo, multinucleated plasma cells.
Modern standards for bone marrow examination according to ICSH guidelines: aspirate morphology, trephine biopsy, flow cytometry, and genetic analysis.
