Oncohematology

Cellular Cannibalism: Entosis in Cytological Diagnosis

What are cellular cannibalism and entosis in malignant tumors: biological mechanisms, cytological signs, and clinical significance of the phenomenon.

Cytological preparation: accumulation of tumor cells with signs of cellular cannibalism
Cytological preparation: accumulation of tumor cells with signs of cellular cannibalism

Cellular Cannibalism 🤤

👉🏾Cellular cannibalism, also called entosis, occurs when one cell surrounds, kills, and digests another. The causes and mechanisms involved in this process are not yet fully known, but it is already known that it is highly malignant.

👉🏾 By devouring neighboring tumor cells, cannibals obtain the energy needed for survival and the emergence of new tumors after treatment. Source: inst:analisesclinicas.pratica