Ring-shaped Leukocyte Nuclei in Peripheral Blood Smears

Holes and ring-shaped nuclei in leukocytes: morphological features of reactive lymphocytes in EBV, granulocyte dysplasia, and differential diagnostics.

Evgeny Zaytsev 1 min June 25, 2025

Blood smear, reactive lymphocyte with a hole in the nucleus in EBV infection

Blood smear, sign of eosinophil dysplasia with a ring-shaped nucleus

Blood smear, granulocyte with a ring-shaped nucleus and granulation

Blood smear, mononuclear cell with rounded defects in the nucleus

A collection of micrographs of human blood cells with holes in the nucleus.

Reactive lymphocyte in EBV infection
Eosinophil dysplasia
Classify independently?
Classify independently?

Read next

Identifying Basophils in Peripheral Blood Smears

Identifying Basophils in Peripheral Blood Smears

Learn to identify basophils in peripheral blood smears: characteristic granulation, nuclear shape, and differential diagnosis from other leukocytes.

Наталья Албекова 1 min

Monocyte Morphology: Atypical Nuclear Shape in Blood Smear

Monocyte Morphology: Atypical Nuclear Shape in Blood Smear

Morphological features of monocytes in peripheral blood smear: variability of nuclear shape, differential diagnosis with other leukocytes.

Editorial team 1 min

Sheep and Goat Leukocyte and Platelet Morphology

Sheep and Goat Leukocyte and Platelet Morphology

Learn about the morphological features of sheep and goat leukocytes and platelets, including identification of neutrophils, lymphocytes, monocytes, and basophils in blood smears.

Editorial team 1 min