Lab test interpretation

Cholesterol Crystals in Pleural Fluid: Microscopic Analysis

Morphology of cholesterol crystals in native pleural fluid: causes, diagnostic significance, and microscopic appearance. A guide for laboratory hematology.

Cholesterol crystals in pleural fluid. Microscopy x200. A 66-year-old male patient from the cardiology department.

🙏 Material kindly provided by biologist of the Clinical Diagnostic Laboratory Tatyana Ivashchenko, Krasnodar.

👉 Reference information: ✅ Cholesterol crystals appear as rectangular plates with a characteristic iridescent appearance and a stepped edge structure. Such crystals are often found in pleural effusions associated with empyema, tuberculosis, or neoplastic processes. Their presence indicates prolonged fluid stasis and cellular element breakdown.