Lab test interpretation

Methotrexate Crystals in Urine with Acute Kidney Injury

Detection of methotrexate crystals in urine sediment with acute kidney injury after high-dose therapy. Features of sediment microscopy.

Urine sediment preparation: massive brown clusters of methotrexate crystals
Urine sediment preparation: massive brown clusters of methotrexate crystals

🔬 Methotrexate crystals in the urine of a patient with acute kidney injury that developed after intravenous administration of large doses of this drug.

👉 Source: Corey Cavanaugh and Mark A. Perazella. Urine Sediment Examination in the Diagnosis and Management of Kidney Disease: Core Curriculum 2019

🙏 Material kindly provided by medical lab technician Dmitry Emelyanov.