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Hematology

Laboratory Diagnostics of Pancytopenia: Blood and Bone Marrow

A case of severe pancytopenia: analyzer results, blood smear morphology, and hypocellular bone marrow aspirate in a 79-year-old patient.

Nana Novikova Nana Novikova 1 min
Peripheral blood smear: erythrocyte anisocytosis and single lymphocytes
Peripheral blood smear: erythrocyte anisocytosis and single lymphocytes
Peripheral blood smear: mononuclear cell against a background of poikilocytosis
Peripheral blood smear: mononuclear cell against a background of poikilocytosis
Peripheral blood smear: neutrophilic granulocyte and erythrocyte poikilocytosis
Peripheral blood smear: neutrophilic granulocyte and erythrocyte poikilocytosis
Bone marrow smear: mononuclear cells with thin cytoplasmic projections
Bone marrow smear: mononuclear cells with thin cytoplasmic projections
Bone marrow smear: hypocellular aspirate with single leukocytes
Bone marrow smear: hypocellular aspirate with single leukocytes
Bone marrow smear: single nucleated cells in the field of view
Bone marrow smear: single nucleated cells in the field of view
Bone marrow smear: mononuclear cell and granulocyte with depleted aspirate
Bone marrow smear: mononuclear cell and granulocyte with depleted aspirate
Bone marrow smear: two mononuclear cells against a background of hypocellularity
Bone marrow smear: two mononuclear cells against a background of hypocellularity
Bone marrow smear: isolated cell in a severely depleted preparation
Bone marrow smear: isolated cell in a severely depleted preparation
Analyzer printout: pancytopenia with WBC 3.2×10⁹/L, HGB 71 g/L, PLT 23×10⁹/L
Analyzer printout: pancytopenia with WBC 3.2×10⁹/L, HGB 71 g/L, PLT 23×10⁹/L

PANCYTOPENIA in a 79-year-old ICU patient. Complete blood count (photos 1,2,3) shows mild anisocytosis and poikilocytosis of erythrocytes. Bone marrow aspirate (photos 5,6,7,8,9) is poor in cellular elements, megakaryocytes are absent, and platelets are few.

🙏 The publication was kindly provided by KDL physician Nana Novikova, CHUZ “CB” RZD-Medicine, Smolensk.

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