Hematology

LE Cells in Blood Smear: Morphology and Formation

What LE cells are in systemic lupus erythematosus: morphological signs of nuclear material phagocytosis by neutrophils in a blood smear.

Blood smear, LE cell: neutrophil with a large phagocytosed LE body
Blood smear, LE cell: neutrophil with a large phagocytosed LE body

🔬Lupus erythematosus cells (LE cells) are neutrophils that have engulfed lymphocyte nuclei, which are coated and denatured by antibodies to nucleoproteins.