Morphology of LE cells in peripheral blood smears in systemic lupus erythematosus: formation mechanism, phagocytosis of nuclear bodies by neutrophils.
🔬 LE cells, peripheral blood. 🙏 Smear photos kindly provided by Kristina Yurievna, clinical laboratory diagnostics physician, BU “RCB”, Cheboksary
📖 Reference information: LE cells (lupus erythematosus cells) are specific cells found in peripheral blood or other tissues in patients with systemic lupus erythematosus (SLE). They are neutrophils or macrophages that have phagocytosed the nuclei of other cells, modified by the action of antinuclear antibodies.
Microscopic view of a peripheral blood smear: unusual flower-like arrangement of neutrophils, leukocyte morphology under light microscopy.
Examples of monocytes with bizarre nuclear shapes in peripheral blood. Morphological features of the monocytic lineage during blood smear microscopy.
Severe cytoplasmic vacuolization of neutrophils in a blood smear from a surgical patient: morphology in severe bacterial infection.
