Oncohematology

Leukemia Cutis: Specific Skin Lesions in Leukemia

Leukemia cutis is the infiltration of the skin by blast cells in acute myeloid leukemia. Clinical variants of skin manifestations include papules, plaques, nodules, and ulcers.

Clinical photos: papular and nodular rashes in leukemia cutis
Clinical photos: papular and nodular rashes in leukemia cutis

Infiltration of the skin by leukemic blast cells, or leukemia cutis, most commonly occurs in monocytic forms of acute myeloid leukemia (AML). Leukemia cutis can also develop in any acute or chronic form of leukemia. As shown in these photographs of AML cases with leukemia cutis, this condition is highly variable and can include widespread papules, nodules, macules, palpable purpura, plaques, or ulcers. Pain and itching are rare. Prepared by: Dermatologist Yulia Sukhoruchko, participant of the Closed Club of Hematologists