Oncohematology

Bone Marrow Lymphocytosis with Normal Blood Counts

A clinical case of atypical lymphocytes in the bone marrow of a patient with weight loss and normal peripheral blood counts. Learn more.

Patient, 47 years old, presented with progressive weight loss and weakness. Lymph nodes and spleen were not enlarged. Complete blood count: RWC 4.5×1012/L, HGB 120g/L, WBC 5.8×109/L, PLT 280×10^9/L, ESR 6 mm/hour. In the bone marrow aspirate, the number of lymphocytes was increased to 23.2% (N 4.3-13.7), with some showing irregular nuclear shapes and being larger than usual. Immunophenotyping and observation were recommended.

🙏 The publication was kindly provided by clinical laboratory physician Nana Novikova, CHUZ “CB” RZD-Medicine, Smolensk.