Oncohematology

Burkitt Lymphoma with CNS Involvement: CSF Cytology

A clinical case of Burkitt lymphoma with CNS involvement: morphology of atypical cells in CSF cytopreparation and flow cytometry results.

Burkitt Lymphoma with CNS involvement. A clinical case from 🇮🇱 Israel. A 58-year-old patient. Peripheral blood showed mild anemia and thrombocytopenia. However, the smear revealed myelocytes, metamyelocytes, band neutrophils, and erythroblasts. (What do we call this condition?)

💡 Bone marrow immunophenotyping shows a 59% population of CD19+Lambda/20+/10+/CD5-.

✅ In images 1,2 below: microscopy of cerebrospinal fluid smears from a patient with total infiltration by pathological lymphoid cells. Smears were prepared using a cytospin apparatus. Image 3: CSF immunophenotyping plots.

🔬The case was kindly shared by the Head of the Morphology/Immunophenotyping Department of the Ha-Emek Medical Center Laboratory, Afula 🇮🇱 Israel - Anna Belen.