Hematology

Macrocytosis and Red Blood Cell Morphology in B12 Deficiency

Peripheral blood smear in vitamin B12 deficiency: severe macrocytosis with MCV 130 fL, megalocytes, poikilocytosis, and nucleated red blood cells.

❗MCV 130 fL 😯 Red blood cells are not just large, they are even comparable in size to neutrophils🧐 (photo 2) Photos 3-5 show red blood cells compared to a lymphocyte. Photo 6 shows a nucleated red blood cell

📝Vitamin B12 deficiency detected

🙏 The publication was kindly provided by the laboratory physician Tanya Stepanova, Volgograd