Megakaryocyte in Peripheral Blood Smear in Leukemia

Clinical case of a megakaryocyte in peripheral blood of a 44-year-old female patient with blastemia (23% blasts), giant platelets, and anemia.

Editorial team 1 min January 23, 2022

Blood smear: megakaryocyte with platelet budding and blasts

Blood smear: group of blast cells and immature granulocytes

Blood smear: binucleated myelocyte with signs of dysplasia

Blood smear: cluster of myeloid precursors and blasts

Blood smear: blast cells and shadows of destroyed leukocytes

Blood smear: two blasts with high nuclear-to-cytoplasmic ratio

Blood smear: blast with delicate chromatin and nucleolus

Blood smear: large blast cell in peripheral blood

WDF scattergram of Sysmex hematology analyzer

Analyzer printout: leukocytosis 20.44, anemia and thrombocytopenia

A case of mythical rarity! Photos from our subscriber. Megakaryocyte in a peripheral blood smear. Female, 44 years old, from a polyclinic, diagnosis not specified. CBC data in the photo, manual count below. A megakaryocyte was found in the peripheral blood, even with platelet budding! Giant platelets and binucleated myelocytes are present. Blasts - 23% Promyelocytes - 3% Myelocytes - 12% Metamyelocytes - 5% Band neutrophils - 5% Segmented neutrophils - 34% Eosinophils - 2% Lymphocytes - 14% Monocytes - 2%