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Hematology

Megakaryocytes in Bone Marrow Aspirate and Thrombopoiesis

Morphological features of megakaryocytes in bone marrow aspirate: assessing megakaryocytopoiesis and visualizing platelet budding in the smear.

Nana Novikova Nana Novikova 1 min
Bone marrow smear: mature megakaryocyte with a polyploid nucleus and abundant cytoplasm
Bone marrow smear: mature megakaryocyte with a polyploid nucleus and abundant cytoplasm
Bone marrow smear: megakaryocyte with a multi-lobed nucleus and cytoplasmic vacuolization
Bone marrow smear: megakaryocyte with a multi-lobed nucleus and cytoplasmic vacuolization
Bone marrow smear: megakaryocyte in the stage of active platelet budding
Bone marrow smear: megakaryocyte in the stage of active platelet budding
Bone marrow smear: platelets detaching from the periphery of the megakaryocyte cytoplasm
Bone marrow smear: platelets detaching from the periphery of the megakaryocyte cytoplasm
Bone marrow smear: megakaryocyte with a segmented nucleus next to a neutrophil
Bone marrow smear: megakaryocyte with a segmented nucleus next to a neutrophil
Bone marrow smear: process of intensive platelet budding by a megakaryocyte
Bone marrow smear: process of intensive platelet budding by a megakaryocyte

MEGAKARYOCYTES in bone marrow aspirate.

The function of megakaryocytopoiesis is platelet formation.

Up to 5 thousand platelets bud off from each megakaryocyte. The lifespan of platelets is about 10 days.

Platelet budding (photos 3,4,6).

🙏 The publication was kindly provided by KDL physician Nana Novikova, CHUZ “Clinical Hospital” RZD-Medicine, Smolensk.

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