👋🏻Let’s get acquainted…MEGALOBLASTS. (marked with red arrows*)
🩸Bone marrow aspirate from a patient with vitamin B12 deficiency.
🧐Asynchronous maturation of the nucleus and cytoplasm is noted. Pronounced hemoglobinization of the cytoplasm (mood color blue😁) while maintaining a delicate chromatin structure.
☝🏻Chromatin condensation occurs unevenly, in clumps (photo 2). Like static on a TV📺, salami sausage🍽️, or sand after a light rain🌧️
➖A cell in mitosis is present (green arrow)
🆘The last photo shows megaloblasts, whose strength and power compressed an innocent erythrocyte.
*Not all megaloblasts are marked, for better perception of all cellular elements. (Without overlapping them)
❓What are your associations with the chromatin in photo 2, or do you use the comparisons presented above in your practice?
🙏 The publication was kindly provided by Clinical Laboratory Diagnostics Doctor Tanya Stepanova, Volgograd
