📸 The photos show bone marrow smears. Infiltration by complexes of atypical cells is notable. Metastatic lesions are possible. 👨⚕ A 35-year-old man presented to a hematologist with complaints of shortness of breath, lower back pain, and leg pain. Diagnosis is pending.
📋 Laboratory tests were concerning: 🩸 Complete Blood Count: — Leukocytes: 8.27 × 10⁹/L — Erythrocytes: 5.24 × 10¹²/L — Hemoglobin: 151 g/L — Platelets: 29 × 10⁹/L (markedly decreased)
🔬 Differential Leukocyte Count: — Myelocytes: 6% — Metamyelocytes: 8% — Band neutrophils: 21% — Segmented neutrophils: 32% — Lymphocytes: 22%, Monocytes: 10%, Basophils: 1%
🧪 Biochemistry: — Total protein: 67 g/L — Urea: 9.2 mmol/L ↑ — Uric acid: 444 µmol/L ↑ — Creatinine: 92 µmol/L
🧫 Immunoglobulins: — IgA: 0.93 g/L — IgM: 1.32 g/L — IgG: 5.47 g/L ↓
➡ The patient was referred to an oncologist. Possible diagnosis — secondary bone marrow involvement - tumor metastasis?
🙏 This clinical case was kindly provided by laboratory physician Yulia Kaliberda, Ekaterinburg.
